Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.62 |
| ▸ | TOP2A | P11388 | 4/20 | 0.58 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.54 |
| ▸ | TK2 | O00142 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8188888 | 1.00 | TK1 (0.62) | TK1TOP2ARNASE1TK2 | |
| SCHEMBL8188889 | 1.00 | TK1 (0.62) | TK1TOP2ARNASE1TK2 | |
| SCHEMBL8176132 | 0.92 | TOP2A (0.55) | TK1TOP2ARNASE1TK2 | |
| SCHEMBL8176129 | 0.92 | TOP2A (0.55) | TK1TOP2ARNASE1TK2 | |
| SCHEMBL8185778 | 0.91 | TOP2A (0.58) | TK1TOP2ARNASE1TK2 | |
| SCHEMBL8185775 | 0.91 | TOP2A (0.58) | TK1TOP2ARNASE1TK2 | |
| SCHEMBL7630823 | 0.91 | TOP2A (0.56) | TK1TOP2ARNASE1TK2 | |
| SCHEMBL8176653 | 0.91 | TOP2A (0.56) | TK1TOP2ARNASE1TK2 | |
| SCHEMBL8176647 | 0.91 | TOP2A (0.56) | TK1TOP2ARNASE1TK2 | |
| SCHEMBL5802542 | 0.89 | POLB (0.55) | TK1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444798-B1 | GENETIC ENGINEERING | BENNER, STEVEN | 2002-09-03 | — | — | US | disclosed |