Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MARK3 | P27448 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968676 | 0.82 | DPP4 (0.60) | KCNA5KCNH2CYP11B1CYP11B2DPP4 | |
| SCHEMBL477401 | 0.81 | KCNA5 (0.51) | KCNA5KCNH2NOTUMCYP11B1CYP11B2 | |
| Methane SCHEMBL28852242 | 0.79 | KCNA5 (0.50) | KCNA5KCNH2NOTUMCYP11B1CYP11B2 | |
| SCHEMBL1129835 | 0.79 | KCNA5 (0.50) | KCNA5KCNH2NOTUMCYP11B1CYP11B2 | |
| SCHEMBL3288611 | 0.79 | DPP4 (0.69) | KCNA5KCNH2NOTUMCYP11B1CYP11B2 | |
| SCHEMBL9289991 | 0.79 | KCNA5 (0.50) | KCNA5KCNH2NOTUMCYP11B1CYP11B2 | |
| SCHEMBL21480329 | 0.79 | KCNA5 (0.59) | KCNA5KCNH2CYP11B1CYP11B2MAPT | |
| SCHEMBL28966771 | 0.78 | KCNA5 (0.49) | KCNA5KCNH2NOTUMCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL14856328 | 0.78 | KCNH2 (0.49) | KCNA5KCNH2NOTUMCYP11B1CYP11B2 | |
| SCHEMBL29712508 | 0.77 | DPP4 (0.41) | DPP4AKT1MAPTLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180200346-A1 | ALBUMIN FUSION PROTEINS | ALBUMEDIX A/S (DK) | 2018-07-19 | — | — | US | disclosed |
| EP-1259526-A2 | NUCLEIC ACIDS, PROTEINS, AND ANTIBODIES | Human Genome Sciences, Inc. (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001055318-A2 | NUCLEIC ACIDS, PROTEINS, AND ANTIBODIES | HUMAN GENOME SCIENCES, INC. (US) | 2001-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180200346-A1 | ALBUMIN FUSION PROTEINS | ALB, FABP1, HDGF | KCNA5 4470/4885KCNH2 4825/4885NOTUM 3959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.