Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.37 |
| ▸ | CCR5 | P51681 | 3/20 | 0.37 |
| ▸ | CCR8 | P51685 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24690 | 0.83 | CCR1 (0.52) | CCR1CCR5CCR8L3MBTL1LMNA | |
| SCHEMBL24520 | 0.71 | CCR1 (0.52) | CCR1CCR5CCR8L3MBTL1LMNA | |
| SCHEMBL1246514 | 0.68 | CCR1 (0.75) | CCR1CCR5CCR8L3MBTL1LMNA | |
| SCHEMBL17511860 | 0.64 | MAPT (0.55) | LMNAKDM4EMAPTTP53HSP90AA1 | |
| SCHEMBL14884158 | 0.63 | KDM4E (0.49) | CCR1CCR5CCR8L3MBTL1LMNA | |
| SCHEMBL14884093 | 0.63 | CYP2A6 (0.49) | CCR1CCR5CCR8L3MBTL1LMNA | |
| SCHEMBL24183839 | 0.63 | LMNA (0.54) | CCR1CCR5CCR8L3MBTL1LMNA | |
| SCHEMBL24183840 | 0.63 | CCR1 (0.61) | CCR1CCR5CCR8L3MBTL1LMNA | |
| SCHEMBL25462076 | 0.62 | CCR1 (0.41) | CCR1CCR5CCR8L3MBTL1LMNA | |
| SCHEMBL29568930 | 0.62 | LMNA (0.58) | CCR1CCR5CCR8L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455579-B1 | Pyran derivatives | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2002-09-24 | — | — | US | disclosed |