Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 5/20 | 0.63 |
| ▸ | CDK1 | P06493 | 5/20 | 0.63 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.63 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.63 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.61 |
| ▸ | RET | P07949 | 3/20 | 0.57 |
| ▸ | EIF2AK2 | P19525 | 4/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 3/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | BCR | P11274 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | PRKACG | P22612 | 1/20 | 0.52 |
| ▸ | PRKACB | P22694 | 1/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259670 | 0.91 | CCNB2 (0.63) | CCNB2CDK1CCNB1CCNB3MAP3K14 | |
| SCHEMBL6254567 | 0.86 | MAP3K14 (0.59) | CCNB2CDK1CCNB1CCNB3MAP3K14 | |
| SCHEMBL6260797 | 0.86 | CCNB2 (0.63) | CCNB2CDK1CCNB1CCNB3MAP3K14 | |
| SCHEMBL31588329 | 0.85 | CCNB2 (0.76) | CCNB2CDK1CCNB1CCNB3MAP3K14 | |
| SCHEMBL144954 | 0.85 | CCNB2 (0.76) | CCNB2CDK1CCNB1CCNB3MAP3K14 | |
| SCHEMBL7626134 | 0.83 | FLT3 (0.67) | CCNB2CDK1CCNB1CCNB3MAP3K14 | |
| SCHEMBL1586801 | 0.82 | CCNB2 (0.67) | CCNB2CDK1CCNB1CCNB3RET | |
| SCHEMBL12723013 | 0.81 | ABL1 (0.58) | CCNB2CDK1CCNB1CCNB3RET | |
| SCHEMBL7662847 | 0.81 | CCNB2 (0.60) | CCNB2CDK1CCNB1CCNB3RET | |
| SCHEMBL12723149 | 0.80 | CCNB2 (0.52) | CCNB2CDK1CCNB1CCNB3MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002102783-A1 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2002-12-27 | — | — | WO | claimed |