Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 6/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | WNT3 | P56703 | 2/20 | 0.47 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.47 |
| ▸ | KHK | P50053 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 1/20 | 0.46 |
| ▸ | FASN | P49327 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488954 | 0.85 | DPP4 (0.64) | HDAC2HPGDDPP4DPP8DPP9 | |
| SCHEMBL1383434 | 0.85 | DPP4 (0.64) | HDAC2HPGDDPP4DPP8DPP9 | |
| SCHEMBL488953 | 0.85 | DPP4 (0.64) | HDAC2HPGDDPP4DPP8DPP9 | |
| SCHEMBL10326191 | 0.84 | DPP4 (0.62) | HPGDTSHRDPP4DPP8DPP9 | |
| SCHEMBL3335449 | 0.84 | DPP4 (0.62) | HPGDTSHRDPP4DPP8DPP9 | |
| SCHEMBL3331450 | 0.84 | DPP4 (0.62) | HPGDTSHRDPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5413834 | 0.84 | DPP4 (0.62) | HDAC2HPGDDPP4DPP8DPP9 | |
| SCHEMBL14548972 | 0.84 | DPP4 (0.62) | HPGDTSHRDPP4DPP8DPP9 | |
| SCHEMBL3332858 | 0.82 | DPP4 (0.64) | HPGDDPP4DPP8DPP9PARP1 | |
| SCHEMBL3332865 | 0.82 | DPP4 (0.64) | HPGDDPP4DPP8DPP9PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020061839-A1 | Serine peptidase modulators | SCHARPE SIMON LODEWIJK (BE) | 2002-05-23 | — | — | US | disclosed |
| EP-1062222-A1 | SERINE PEPTIDASE MODULATORS | Fondatech Benelux N.V. (BE) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999046272-A1 | SERINE PEPTIDASE MODULATORS | FONDATECH BENELUX N.V. (BE) | 1999-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061839-A1 | Serine peptidase modulators | FAP, CTSC, DPP4 | HDAC2 879/4885HPGD 1509/4885TSHR 3714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.