Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | CNR2 | P34972 | 8/20 | 0.67 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 4/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620511 | 1.00 | FAAH (0.69) | FAAHMEN1KMT2AMAPK1CNR2 | |
| SCHEMBL7626029 | 1.00 | FAAH (0.69) | FAAHMEN1KMT2AMAPK1CNR2 | |
| SCHEMBL7622731 | 1.00 | FAAH (0.69) | FAAHMEN1KMT2AMAPK1CNR2 | |
| SCHEMBL7773497 | 1.00 | FAAH (0.69) | FAAHMEN1KMT2AMAPK1CNR2 | |
| SCHEMBL7628966 | 1.00 | FAAH (0.69) | FAAHMEN1KMT2AMAPK1CNR2 | |
| SCHEMBL14047277 | 1.00 | FAAH (0.69) | FAAHMEN1KMT2AMAPK1CNR2 | |
| SCHEMBL24193796 | 1.00 | FAAH (0.69) | FAAHMEN1KMT2AMAPK1CNR2 | |
| SCHEMBL7621556 | 1.00 | FAAH (0.69) | FAAHMEN1KMT2AMAPK1CNR2 | |
| SCHEMBL7619801 | 1.00 | FAAH (0.69) | FAAHMEN1KMT2AMAPK1CNR2 | |
| SCHEMBL7625996 | 1.00 | FAAH (0.69) | FAAHMEN1KMT2AMAPK1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444832-B1 | OSTEOPOROSIS | ESSWEIN ANGELIKA (DE) | 2002-09-03 | — | — | US | disclosed |