Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL762443 | 0.93 | MAPT (0.48) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| SCHEMBL18713238 | 0.86 | MAPT (0.59) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| SCHEMBL13261241 | 0.84 | MAPT (0.53) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| SCHEMBL12082337 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1MAPTRAB9A | |
| SCHEMBL14905181 | 0.81 | MAPT (0.42) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL1924408 | 0.81 | TDP1 (0.52) | ALDH1A1TSHRALOX15MAPK1CYP3A4 | |
| SCHEMBL6880339 | 0.81 | ESR1 (0.42) | ALDH1A1TSHRALOX15HSD17B10MAPK1 | |
| SCHEMBL6859648 | 0.81 | CHRM1 (0.42) | ALDH1A1ALOX15HSD17B10MAPTKDM4E | |
| SCHEMBL8279450 | 0.81 | TAAR1 (0.43) | ALDH1A1MAPK1TDP1MAPTKDM4E | |
| SCHEMBL1432529 | 0.81 | TAAR1 (0.43) | ALDH1A1MAPTKDM4ECYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138303-B2 | Polymers | BASF SE (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20100249349-A1 | Novel Polymers | UDC IRELAND LIMITED (IE) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249349-A1 | Novel Polymers | OCIAD2, OCIAD1, SLCO4C1 | ALDH1A1 478/4885TSHR 4848/4885ALOX15 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.