Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7624656 | 0.73 | SLC6A4 (0.40) | SLC6A4SLC6A3SLC6A2GAACASP1 | |
| SCHEMBL22366787 | 0.73 | SLC6A4 (0.40) | SLC6A4SLC6A3SLC6A2GAACASP1 | |
| SCHEMBL20403011 | 0.71 | SLC6A4 (0.39) | SLC6A4SLC6A3SLC6A2GAACASP1 | |
| SCHEMBL13290389 | 0.71 | SLC6A4 (0.39) | SLC6A4SLC6A3SLC6A2GAACASP1 | |
| SCHEMBL6585726 | 0.71 | — | — | |
| SCHEMBL6588538 | 0.71 | — | — | |
| SCHEMBL4441642 | 0.71 | — | — | |
| SCHEMBL18734584 | 0.70 | SLC6A4 (0.37) | SLC6A4SLC6A3SLC6A2GAACASP1 | |
| Diethylamine SCHEMBL4083176 | 0.69 | — | — | |
| SCHEMBL24842182 | 0.68 | SLC6A4 (0.36) | SLC6A4SLC6A3SLC6A2GAACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444677-B2 | TREATMENT OF INFLAMMATION, CARDIOVASCULAR DISEASE, PAIN, ETC. | PFIZER INC. | 2002-09-03 | — | — | US | disclosed |
| EP-1106614-A1 | 5-Membered heteroaryl substituted 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER INC. (US) | 2001-06-13 | — | — | EP | disclosed |