SCHEMBL7624765

SCHEMBL7624765

N#CSCSc1nc2c(Cl)c(Cl)c(Cl)c(Cl)c2s1

nearest known ligand 0.30

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9386156 0.71 PSMB8 (0.52) ALDH1A1MAPK1SMN1; SMN2HIF1AHSD17B10
SCHEMBL9058700 0.68 KMT2A (0.56) ALDH1A1TP53HPGDTSHRMAPK1
SCHEMBL1414529 0.65 CYP1A2 (0.42) ALDH1A1HPGDTSHRMAPK1SMN1; SMN2
SCHEMBL8734335 0.63 CYP1A2 (0.34) MAPK1HIF1A
SCHEMBL29352673 0.62 CYP1A2 (0.73) ALDH1A1HPGDTSHRMAPK1SMN1; SMN2
SCHEMBL8887013 0.62 CYP1A2 (0.73) ALDH1A1HPGDTSHRMAPK1SMN1; SMN2
SCHEMBL54175 0.62 CYP1A2 (0.73) ALDH1A1HPGDTSHRMAPK1SMN1; SMN2
SCHEMBL11668426 0.62 PDK1 (0.54) ALDH1A1TP53TSHRSMN1; SMN2HSD17B10
SCHEMBL8575765 0.61 GAA (0.47) ALDH1A1
SCHEMBL11544351 0.61 TDP1 (0.39) ALDH1A1TP53HPGDTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002059221-A2 ANTIFOULING AGENT COMPRISING A N-PHENYL-N'-2,6-DIFLUOROBENZOYL UREA DERIVATIVE SDS BIOTECH K.K. (JP) 2002-08-01 WO disclosed
EP-0712576-B1 Antifouling agent ASAHI DENKA KOGYO KK (JP) 2000-10-11 EP disclosed
EP-0635209-B1 AQUATIC PEST CONTROL DRUG ASAHI DENKA KOGYO KK (JP) 2000-05-17 EP disclosed
EP-0712576-A1 Antifouling agent ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1996-05-22 EP disclosed
US-5505770-A CONTAINING AT LEAST ONE ALKYLPHENYL ESTER OF PHOSPHOROUS OR PHOSPHORIC ACID ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1996-04-09 US disclosed
US-5472483-A Polysulfide compounds with carriers for protective coating of underwater structures ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1995-12-05 US disclosed
EP-0635209-A1 AQUATIC PEST CONTROL DRUG ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1995-01-25 EP disclosed
EP-0273457-B1 ANTIFOULING PAINT NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1992-07-08 EP disclosed
US-4898895-A Antifouling pain having a polyacrylate component with pendent silyl or siloxane groups NIPPON OIL AND FATS CO., LTD. (JP) 1990-02-06 US disclosed
EP-0273457-A2 Antifouling paint NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-07-06 EP disclosed