SCHEMBL7625019

SCHEMBL7625019

CC1CCC(C)[C](OOC(=O)c2ccc([Si](C)(C)C)cc2)C1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.31
ALDH1A1 P00352 1/20 0.31
THRB P10828 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7635017 0.87 NR1H2 (0.32)
SCHEMBL7630503 0.87
SCHEMBL7633622 0.85 NPC1 (0.33)
SCHEMBL7631864 0.85 TDP1 (0.41) MAPTALDH1A1SMN1; SMN2
SCHEMBL7633347 0.83 LMNA (0.46) MAPTALDH1A1SMN1; SMN2
SCHEMBL7631142 0.83 POLB (0.40) MAPTALDH1A1SMN1; SMN2
SCHEMBL7631016 0.83 CA1 (0.45) MAPTALDH1A1SMN1; SMN2
SCHEMBL7631618 0.82 SCN1A (0.44) MAPTSMN1; SMN2
SCHEMBL7623912 0.82 POLB (0.42) ALDH1A1SMN1; SMN2
SCHEMBL7627365 0.82 TP53 (0.41) MAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed