SCHEMBL7625313

SCHEMBL7625313

COC1CCCCN1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16454010 1.00
SCHEMBL9024964 1.00
SCHEMBL21900849 0.98 CYP1A2 (0.41)
SCHEMBL4774239 0.92
SCHEMBL3569489 0.92
SCHEMBL1644988 0.92
SCHEMBL27965922 0.84 CHRNB2 (0.31)
SCHEMBL23747471 0.81
SCHEMBL28106678 0.78 CYP1A2 (0.33)
Benzoic Acid SCHEMBL8188955 0.77 CHRNB2 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240279215-A1 NAMPT MODULATORS CYTOKINETICS, INCORPORATED 2024-08-22 US disclosed
US-20230287004-A1 SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES AND PRODRUGS THEREOF SHIONOGI & CO., LTD. (JP) 2023-09-14 US disclosed
WO-2023114188-A1 IONIZABLE LIPIDS AND COMPOSITIONS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-06-22 WO disclosed
US-20180118760-A1 SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES AND PRODRUGS THEREOF SHIONOGI & CO., LTD. (JP) 2018-05-03 US disclosed
US-20170260158-A1 QUINOLINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO THE MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR AbbVie Deutschland GmbH & Co. KG (DE) 2017-09-14 US disclosed
CN-103249737-B Borate as arginase inhibitor 马尔斯公司 2016-06-08 CN disclosed
CN-103562210-B PI3K 110 δ are had to optionally benzo oxygen azepine * compound and using method F. HOFFMANN-LA ROCHE AG (CH) 2016-05-25 CN disclosed
US-9145377-B2 G-quadruplex stabilising agent UNIVERSITY COLLEGE LONDON (GB) 2015-09-29 US disclosed
CN-104725397-A Thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them SERVIER LAB 2015-06-24 CN disclosed
CN-102471312-B 6-aminoquinazoline or 3-cyanoquinoline derivatives, preparation method and medical application thereof JIANGSU HENGRUI MEDICINE CO 2014-06-18 CN disclosed
CN-1258294-A 2-oxoimidazole derivs. BANYU PHARMA CO LTD (JP) 2000-06-28 CN disclosed
US-6071906-A INHIBITS OR MODULATES THE INDUCIBLE ISOFORM OF NITRIC OXIDE SYNTHASE OVER THE THE CONSTITUTIVE ISOFORMS; ANTIARTHRITIC, -DIABETIC, ISCHEMIC, THROMBOSIS AGENTS; CARDIOVASCULAR DISORDERS; TOXIC SHOCK SYNDROME; AUTOIMMUNE DISEASES G. D. SEARLE & CO. (US) 2000-06-06 US disclosed
US-6046211-A TREATMENT OF ARTHRITIS OR INFLAMMATORY BOWEL DISEASE, CARDIOVASCULAR ISCHEMIA, DIABETES, HYPERALGESIA (ALLODYNIA), CEREBRAL ISCHEMIA AND OTHER CNS DISORDERS G.D. SEARLE & CO. (US) 2000-04-04 US disclosed
EP-0724570-B1 AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS SEARLE & CO (US) 1999-03-03 EP disclosed
EP-0897912-A1 Amidino derivatives useful as nitric oxide synthase inhibitors G.D. SEARLE & CO. (US) 1999-02-24 EP disclosed
US-5854234-A Amidino dervatives useful as nitric oxide synthase inhibitors G. D. SEARLE & CO. (US) 1998-12-29 US disclosed
EP-0724570-A1 AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS G.D. SEARLE & CO. (US) 1996-08-07 EP disclosed
WO-1995011231-A1 AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS G. D. SEARLE & CO. (US) 1995-04-27 WO disclosed
WO-1993024468-A1 PYRIMIDINYL- AND TRIAZINYL- SALICYL- AND PICOLYLAMIDES AND THE USE, AS HERBICIDES, AND PREPARATION THEREOF CIBA-GEIGY AG (CH) 1993-12-09 WO disclosed
CN-1069272-A The method for preparing benzo pyrrole or thiapyran and pyrazoles BOOTS CO PLC (GB) 1993-02-24 CN disclosed