Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7634394 | 0.87 | PARP1 (0.46) | PARP1TDP1HPGDHDAC8HDAC6 | |
| SCHEMBL7629476 | 0.84 | ADRB2 (0.44) | PARP1TDP1HPGDHDAC8HDAC6 | |
| SCHEMBL29397067 | 0.84 | PARP1 (0.61) | PARP1TDP1HPGDHDAC8HDAC6 | |
| SCHEMBL44313 | 0.84 | PARP1 (0.61) | PARP1TDP1HPGDHDAC8HDAC6 | |
| SCHEMBL7623869 | 0.83 | PARP1 (0.42) | PARP1TDP1HPGDHDAC8HDAC6 | |
| SCHEMBL6972310 | 0.83 | NPC1 (0.55) | PARP1TDP1HPGDHDAC8HDAC6 | |
| SCHEMBL7636613 | 0.82 | TPMT (0.43) | TDP1HPGDNPC1RAB9AKMT2A | |
| SCHEMBL7630658 | 0.82 | HDAC8 (0.43) | PARP1TDP1HPGDHDAC8HDAC6 | |
| SCHEMBL7628661 | 0.82 | HDAC8 (0.43) | PARP1TDP1HPGDHDAC8HDAC6 | |
| SCHEMBL7633324 | 0.82 | HDAC8 (0.43) | PARP1TDP1HPGDHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233014-A1 | ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME | NOF CORPORATION (JP) | 2002-08-21 | — | — | EP | disclosed |