Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26979799 | 0.85 | THRB (0.48) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL18492454 | 0.85 | THRB (0.48) | THRBTSHRTET2POLBAPEX1 | |
| SCHEMBL3688925 | 0.84 | THRB (0.52) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL18051644 | 0.84 | THRB (0.52) | THRBTSHRPOLBAPEX1HTT | |
| Ammonia Solution, Strong SCHEMBL18492403 | 0.83 | THRB (0.47) | THRBTSHRPOLBAPEX1HTT | |
| Ammonia Solution, Strong SCHEMBL19133680 | 0.83 | THRB (0.47) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL4952891 | 0.82 | THRB (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL11330737 | 0.82 | THRB (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL8965485 | 0.82 | THRB (0.53) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL438464 | 0.82 | THRB (0.53) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214361-A1 | TEMPERATURE SENSITIVE POLYMERS | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2002-06-19 | — | — | EP | claimed |
| WO-2001009198-A1 | TEMPERATURE SENSITIVE POLYMERS | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2001-02-08 | — | — | WO | claimed |
| EP-1072617-A1 | Temperature sensitive polymers | Universiteit van Utrecht (NL) | 2001-01-31 | — | — | EP | claimed |
| EP-1214361-A1 | TEMPERATURE SENSITIVE POLYMERS | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001009198-A1 | TEMPERATURE SENSITIVE POLYMERS | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2001-02-08 | — | — | WO | disclosed |
| EP-1072617-A1 | Temperature sensitive polymers | Universiteit van Utrecht (NL) | 2001-01-31 | — | — | EP | disclosed |