SCHEMBL7626008

SCHEMBL7626008

COc1cc(C(=O)OO[C]2CCCC2)cc(OC)c1OC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.51
KMT2A Q03164 6/20 0.51
SMN1; SMN2 Q16637 4/20 0.48
TSHR P16473 2/20 0.48
SLC29A1 Q99808 4/20 0.47
MAPT P10636 1/20 0.47
LMNA P02545 2/20 0.45
ABCC4 O15439 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CHRM3 P20309 1/20 0.45
HTR2A P28223 1/20 0.45
MAPK1 P28482 1/20 0.45
SLC6A4 P31645 1/20 0.45
CYP2C19 P33261 1/20 0.45
SCN1A P35498 1/20 0.45
THPO P40225 1/20 0.45
HTR2B P41595 1/20 0.45
MTOR P42345 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7629964 0.98 MEN1 (0.50) MEN1KMT2ASMN1; SMN2TSHRSLC29A1
SCHEMBL7625836 0.98 MEN1 (0.50) MEN1KMT2ASMN1; SMN2TSHRSLC29A1
SCHEMBL7631634 0.83 MAPT (0.56) MEN1KMT2ASMN1; SMN2TSHRMAPT
SCHEMBL7626059 0.82 MEN1 (0.44) MEN1KMT2ASMN1; SMN2TSHRSLC29A1
SCHEMBL7628166 0.82 MAPT (0.55) MEN1KMT2ASMN1; SMN2TSHRMAPT
SCHEMBL7629419 0.82 MAPT (0.55) MEN1KMT2ASMN1; SMN2TSHRMAPT
SCHEMBL7635175 0.81 MEN1 (0.42) MEN1KMT2ATSHRMAPTLMNA
SCHEMBL7627577 0.79 KMT2A (0.44) MEN1KMT2ATSHRMAPTLMNA
SCHEMBL7633497 0.79 KMT2A (0.44) MEN1KMT2ATSHRMAPTLMNA
SCHEMBL7623494 0.77 MEN1 (0.42) MEN1KMT2ALMNACYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed