SCHEMBL7635175

SCHEMBL7635175

COc1cc(OC)cc(C(=O)OO[C]2CCCC2)c1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
KDM4E B2RXH2 3/20 0.41
MAPT P10636 2/20 0.41
TSHR P16473 2/20 0.39
GAA P10253 2/20 0.38
ABCG2 Q9UNQ0 1/20 0.38
FLT3 P36888 1/20 0.38
LMNA P02545 1/20 0.38
EGFR P00533 1/20 0.37
ALDH1A1 P00352 2/20 0.37
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7633497 0.98 KMT2A (0.44) MEN1KMT2AKDM4EMAPTTSHR
SCHEMBL7627577 0.98 KMT2A (0.44) MEN1KMT2AKDM4EMAPTTSHR
SCHEMBL7635399 0.84 ESR1 (0.55) MEN1KMT2ATSHRALDH1A1CASP3
SCHEMBL7628693 0.83 CA1 (0.55) MEN1KMT2AKDM4EMAPTLMNA
SCHEMBL7627531 0.83 ESR1 (0.54) MEN1KMT2ATSHRALDH1A1CASP3
SCHEMBL7627175 0.83 ESR1 (0.54) MEN1KMT2ATSHRALDH1A1CASP3
SCHEMBL7630276 0.82 CA1 (0.53) MEN1KMT2AKDM4EMAPTLMNA
SCHEMBL7633045 0.82 CA1 (0.53) MEN1KMT2AKDM4EMAPTLMNA
SCHEMBL7625138 0.81 KMT2A (0.39) MEN1KMT2AKDM4EMAPTTSHR
SCHEMBL7626008 0.81 MEN1 (0.51) MEN1KMT2AMAPTTSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed