Thioglycolic Acid

Thioglycolic Acid

SCHEMBL7626010

O=C(O)CS.O=C(O)CS.O=C(O)CS.O=C(O)CS.S.S

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.43
LDHA P00338 1/20 0.43
SRR Q9GZT4 1/20 0.43
ALKBH5 Q6P6C2 1/20 0.43
SUCNR1 Q9BXA5 1/20 0.43
EGLN1 Q9GZT9 1/20 0.43
FOLH1 Q04609 1/20 0.42
TSHR P16473 5/20 0.40
FFAR3 O14843 1/20 0.40
GLRA1 P23415 1/20 0.40
SLC6A9 P48067 1/20 0.40
OR51E2 Q9H255 1/20 0.40
ACE P12821 1/20 0.40
SLC22A6 Q4U2R8 1/20 0.38
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 1/20 0.37
APEX1 P27695 1/20 0.37
CYP2D6 P10635 3/20 0.35
CYP2C19 P33261 1/20 0.35
NFKB1 P19838 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thioglycolic Acid SCHEMBL2914462 1.00 LMNA (0.43) LMNALDHASRRALKBH5SUCNR1
Thioglycolic Acid SCHEMBL10424203 1.00
Thioglycolic Acid SCHEMBL10956970 0.96
Thioglycolic Acid SCHEMBL10954860 0.96 LMNA (0.40) LMNALDHASRRALKBH5SUCNR1
Thioglycolic Acid SCHEMBL21581908 0.96
Thioglycolic Acid SCHEMBL21017 0.95
Thioglycolic Acid SCHEMBL134322 0.95 LMNA (0.46) LMNALDHASRRALKBH5SUCNR1
Thioglycolic Acid SCHEMBL9357348 0.91
Thioglycolic Acid SCHEMBL7033331 0.91
Thioglycolic Acid SCHEMBL60835 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6447656-B1 Biosensor AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 2002-09-10 US disclosed
US-6417009-B1 COUPLING LIPID AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY INSTITUTE (AU) 2002-07-09 US disclosed
EP-0986747-A4 IMPROVED BIOSENSOR AU MEMBRANE & BIOTECH RES INST (AU) 2001-07-25 EP disclosed
EP-0986747-A1 IMPROVED BIOSENSOR AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 2000-03-22 EP disclosed
WO-1999026591-A2 IMPROVED HAIR PERMING AGENT SDG, INC. (US) 1999-06-03 WO disclosed
EP-0912546-A1 IMPROVED RESERVOIR COMPONENTS AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 1999-05-06 EP disclosed
WO-1998055854-A1 IMPROVED BIOSENSOR AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 1998-12-10 WO disclosed
WO-1997043274-A1 IMPROVED RESERVOIR COMPONENTS AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 1997-11-20 WO disclosed
WO-1997025616-A1 ION CHANNEL SENSOR TYPING AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) 1997-07-17 WO disclosed