Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | CETP | P11597 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7626523 | 0.83 | FAAH (0.67) | LMNAMAPTFAAHMEN1KMT2A | |
| SCHEMBL7627348 | 0.83 | FAAH (0.67) | LMNAMAPTFAAHMEN1KMT2A | |
| SCHEMBL7629918 | 0.83 | FAAH (0.67) | LMNAMAPTFAAHMEN1KMT2A | |
| SCHEMBL7629944 | 0.83 | FAAH (0.67) | LMNAMAPTFAAHMEN1KMT2A | |
| SCHEMBL7623304 | 0.83 | FAAH (0.67) | LMNAMAPTFAAHMEN1KMT2A | |
| SCHEMBL7626822 | 0.83 | FAAH (0.67) | LMNAMAPTFAAHMEN1KMT2A | |
| SCHEMBL7623325 | 0.83 | FAAH (0.67) | LMNAMAPTFAAHMEN1KMT2A | |
| SCHEMBL7624407 | 0.83 | FAAH (0.67) | LMNAMAPTFAAHMEN1KMT2A | |
| SCHEMBL7621285 | 0.83 | FAAH (0.67) | LMNAMAPTFAAHMEN1KMT2A | |
| SCHEMBL3879333 | 0.80 | FAAH (0.61) | LMNAMAPTFAAHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444832-B1 | OSTEOPOROSIS | ESSWEIN ANGELIKA (DE) | 2002-09-03 | — | — | US | disclosed |