Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7627436 | 0.89 | CRHR1 (0.89) | CRHR1 | |
| SCHEMBL7624832 | 0.87 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL7622284 | 0.86 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL8202273 | 0.84 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL7623363 | 0.83 | CRHR1 (0.72) | CRHR1 | |
| SCHEMBL23625461 | 0.82 | CRHR1 (0.69) | CRHR1 | |
| SCHEMBL7474752 | 0.81 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL8044612 | 0.81 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL30079862 | 0.81 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL7619639 | 0.81 | CRHR1 (1.00) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448261-B1 | CORTICOTROPIN RELEASING FACTOR ANTAGONISTS; TREATING ANXIETY, DEPRESSION, AND OTHER PSYCHIATRIC AND NEUROLOGICAL DISORDERS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-09-10 | — | — | US | disclosed |
| US-6107300-A | CORTICOTROPIN RELEASING FACTOR ANTAGONIST; PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS (US) | 2000-08-22 | — | — | US | disclosed |