⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15472442 | 0.75 | ADORA1 (0.40) | — | |
| SCHEMBL12297563 | 0.72 | — | — | |
| SCHEMBL8011310 | 0.72 | — | — | |
| SCHEMBL3666602 | 0.72 | — | — | |
| SCHEMBL13134337 | 0.72 | MAPT (0.44) | — | |
| SCHEMBL8786846 | 0.70 | L3MBTL1 (0.39) | — | |
| SCHEMBL6617108 | 0.70 | — | — | |
| SCHEMBL3520851 | 0.69 | PDE3B (0.47) | — | |
| SCHEMBL14156244 | 0.69 | POLB (0.33) | — | |
| SCHEMBL1781531 | 0.69 | ADORA2A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12454529-B2 | Piperazine cyclic ureas | Sironax Ltd. (KY) | 2025-10-28 | — | — | US | disclosed |
| US-20250026759-A1 | TETRAHYDROQUINAZOLINE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS | MERCK SHARP & DOHME LLC (US) | 2025-01-23 | — | — | US | disclosed |
| CN-115697991-B | Piperazine cyclic ureas | 维泰瑞隆有限公司 | 2024-11-22 | — | — | CN | disclosed |
| US-20230203019-A1 | Piperazine Cyclic Ureas | SIRONAX (BEIJING) CO., LTD. (CN) | 2023-06-29 | — | — | US | disclosed |
| US-20230203019-A1 | Piperazine Cyclic Ureas | SIRONAX (BEIJING) CO., LTD. (CN) | 2023-06-29 | — | — | US | disclosed |
| US-20230203019-A1 | Piperazine Cyclic Ureas | SIRONAX (BEIJING) CO., LTD. (CN) | 2023-06-29 | — | — | US | disclosed |
| WO-2023088426-A1 | OXOBUTAN(-2-ENOIC ACID) ACID COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF, AND HERBICIDE | 南开大学 | 2023-05-25 | — | — | WO | disclosed |
| CN-115697991-A | Piperazine cyclic ureas | 维泰瑞隆有限公司 | 2023-02-03 | — | — | CN | disclosed |
| WO-2022115384-A1 | TRICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2022-06-02 | — | — | WO | disclosed |
| WO-2021163727-A1 | PIKFYVE KINASE INHIBITORS | AcuraStem Incorporated (US) | 2021-08-19 | — | — | WO | disclosed |
| US-5550244-A | Process for preparing sulphonylaminocarbonyltriazolinones | BAYER AKTIENGESELLSCHAFT (DE) | 1996-08-27 | — | — | US | disclosed |
| WO-1995027703-A1 | SUBSTITUTED SULPHONYLAMINOCARBONYLTRIAZOLINONES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-19 | — | — | WO | disclosed |
| EP-0341489-B1 | Sulfonyl amino carbonyl triazolinones | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |
| EP-0664797-A1 | SULPHONYL AMINO CARBONYL TRIAZOLINONES. | BAYER AG (DE) | 1995-08-02 | — | — | EP | disclosed |
| EP-0659746-A1 | Process for the preparation of sulfonylaminocarbonyl-triazolinones | BAYER AG (DE) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994008979-A1 | SULPHONYL AMINO CARBONYL TRIAZOLINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-28 | — | — | WO | disclosed |
| EP-0298371-B1 | SUBSTITUTED TRIAZOLINONES | BAYER AG (DE) | 1991-10-02 | — | — | EP | disclosed |
| US-4948417-A | POSTEMERGENCE | BAYER AKTIENGESELLSCHAFT (DE) | 1990-08-14 | — | — | US | disclosed |
| EP-0341489-A1 | Sulfonyl amino carbonyl triazolinones | BAYER AG (DE) | 1989-11-15 | — | — | EP | disclosed |
| EP-0298371-A1 | Substituted triazolinones | BAYER AG (DE) | 1989-01-11 | — | — | EP | disclosed |