Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | EEF2K | O00418 | 2/20 | 0.44 |
| ▸ | EEF2 | P13639 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908393 | 0.95 | HTT (0.44) | CA1CA2EEF2KEEF2MEN1 | |
| SCHEMBL1533960 | 0.84 | HTT (0.45) | CA1CA2MEN1KMT2AHTT | |
| SCHEMBL23004261 | 0.83 | MEN1 (0.44) | CA1CA2EEF2KEEF2MEN1 | |
| SCHEMBL28808933 | 0.83 | HTT (0.47) | CA1CA2MEN1KMT2AHTT | |
| SCHEMBL11785042 | 0.82 | CA1 (0.41) | CA1CA2EEF2KEEF2MEN1 | |
| Sulfuric Acid SCHEMBL3006216 | 0.82 | KMT2A (0.40) | CA1CA2EEF2KEEF2MEN1 | |
| SCHEMBL5287245 | 0.82 | KMT2A (0.55) | CA1CA2EEF2KEEF2MEN1 | |
| SCHEMBL4240591 | 0.82 | KMT2A (0.55) | CA1CA2EEF2KEEF2MEN1 | |
| SCHEMBL372335 | 0.82 | KMT2A (0.55) | CA1CA2EEF2KEEF2MEN1 | |
| SCHEMBL1826845 | 0.82 | KMT2A (0.55) | CA1CA2EEF2KEEF2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769517-B1 | SURFACE-MODIFIED FLUORORESIN MOLDED PRODUCT | DAIKIN IND LTD (JP) | 2002-09-18 | — | — | EP | disclosed |
| US-5684065-A | LASER BEAM | DAIKIN INDUSTRIES, LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0769517-A1 | SURFACE-MODIFIED FLUORORESIN MOLDED PRODUCT | DAIKIN INDUSTRIES, LTD. (JP) | 1997-04-23 | — | — | EP | disclosed |
| US-3931129-A | FLUOROELASTOMER COMPOSITION | DAIKIN KOGYO CO., LTD. (JA) | 1976-01-06 | — | — | US | disclosed |