SCHEMBL7628264

SCHEMBL7628264

[CH2]CCCCCCCCCC[C](OOC(=O)c1cc(OC)cc(OC)c1)OOC(=O)c1cc(OC)cc(OC)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 4/20 0.40
HDAC8 Q9BY41 4/20 0.40
HDAC3 O15379 2/20 0.40
HDAC4 P56524 2/20 0.40
HDAC7 Q8WUI4 2/20 0.40
HDAC2 Q92769 2/20 0.40
HDAC10 Q969S8 2/20 0.40
HDAC11 Q96DB2 2/20 0.40
HDAC6 Q9UBN7 2/20 0.40
HDAC9 Q9UKV0 2/20 0.40
HDAC5 Q9UQL6 2/20 0.40
KDM4E B2RXH2 2/20 0.37
GAA P10253 1/20 0.37
RXRA P19793 1/20 0.36
KMT2A Q03164 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.34
PKM P14618 1/20 0.34
FFAR1 O14842 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7630103 1.00 HDAC1 (0.40) HDAC1HDAC8HDAC3HDAC4HDAC7
SCHEMBL7630431 0.99 HDAC3 (0.39) HDAC1HDAC8HDAC3HDAC4HDAC7
SCHEMBL7631341 0.94 KDM4E (0.39) HDAC1HDAC8HDAC3HDAC4HDAC7
SCHEMBL7632323 0.88 GAA (0.41) KDM4EGAARXRAKMT2AL3MBTL1
SCHEMBL7633394 0.87 CES2 (0.48) HDAC1HDAC6KMT2AMEN1SMN1; SMN2
SCHEMBL7628496 0.87 CES2 (0.48) HDAC1HDAC6KMT2AMEN1SMN1; SMN2
SCHEMBL7633514 0.86 CA1 (0.47) HDAC1HDAC8HDAC3HDAC4HDAC7
SCHEMBL7625496 0.86 CA1 (0.47) HDAC1HDAC8HDAC3HDAC4HDAC7
SCHEMBL7635690 0.86 CA1 (0.47) HDAC1HDAC8HDAC3HDAC4HDAC7
SCHEMBL7627332 0.86 CA1 (0.47) HDAC1HDAC8HDAC3HDAC4HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed