SCHEMBL7628478

SCHEMBL7628478

CO/C=C(/C(=O)O)c1ccccc1COc1cccc(O)c1

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 7/20 0.57
NPC1 O15118 1/20 0.41
NR4A2 P43354 1/20 0.41
RAB9A P51151 1/20 0.41
CYP3A4 P08684 1/20 0.41
CAPN1 P07384 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8639304 0.90 KDM4E (0.47) HIF1ANR4A2CAPN1
SCHEMBL7171491 0.89 HIF1A (0.65) HIF1ACYP3A4
SCHEMBL7171493 0.89 HIF1A (0.65) HIF1ACYP3A4
SCHEMBL9894889 0.89 HIF1A (0.65) HIF1ACYP3A4
SCHEMBL7622442 0.86 HIF1A (0.49) HIF1ANPC1NR4A2RAB9ACYP3A4
SCHEMBL28681565 0.85 HIF1A (0.43) HIF1ANPC1NR4A2RAB9ACAPN1
SCHEMBL8083996 0.83 HIF1A (0.41) HIF1ANPC1NR4A2RAB9A
SCHEMBL8083999 0.83 HIF1A (0.41) HIF1ANPC1NR4A2RAB9A
SCHEMBL28684364 0.82 PARP10 (0.43) HIF1A
SCHEMBL8015684 0.82 HIF1A (0.47) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6444850-B1 PLANTS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2002-09-03 US disclosed