Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5154473 | 0.95 | — | — | |
| Bicarbonate SCHEMBL10451074 | 0.95 | CA1 (0.56) | — | |
| Bicarbonate SCHEMBL7118766 | 0.90 | — | — | |
| Bicarbonate SCHEMBL11728075 | 0.90 | — | — | |
| Bicarbonate SCHEMBL28321876 | 0.90 | — | — | |
| Bicarbonate SCHEMBL27856188 | 0.86 | — | — | |
| Oxalic Acid SCHEMBL11647373 | 0.86 | CA1 (0.46) | — | |
| Formic Acid SCHEMBL16108323 | 0.84 | ALDH1A1 (0.33) | — | |
| Formic Acid SCHEMBL741409 | 0.84 | — | — | |
| Formic Acid SCHEMBL8351086 | 0.84 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242067-A2 | CALCIUM FORMATE FOR USE AS A PHOSPHORUS BINDER AND A DIETARY SUPPLEMENT | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001045695-A2 | CALCIUM FORMATE FOR USE AS A PHOSPHORUS BINDER AND A DIETARY SUPPLEMENT | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2001-06-28 | — | — | WO | disclosed |