Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3819275 | 0.89 | FFAR1 (0.44) | FFAR1NLRP3MEN1KMT2ANPC1 | |
| SCHEMBL27810153 | 0.85 | ALDH1A1 (0.46) | TSHRALDH1A1FFAR1NLRP3MEN1 | |
| SCHEMBL5972758 | 0.82 | TSHR (0.48) | TSHRALDH1A1NLRP3MEN1KMT2A | |
| SCHEMBL10249906 | 0.81 | TSHR (0.47) | TSHRALDH1A1NLRP3MEN1KMT2A | |
| SCHEMBL2320013 | 0.81 | ALDH1A1 (0.47) | TSHRALDH1A1NLRP3MEN1KMT2A | |
| SCHEMBL12499810 | 0.81 | ALDH1A1 (0.47) | TSHRALDH1A1NLRP3MEN1KMT2A | |
| SCHEMBL3821109 | 0.81 | FFAR1 (0.51) | TSHRALDH1A1FFAR1MEN1KMT2A | |
| SCHEMBL6108621 | 0.81 | CA12 (0.41) | TSHRALDH1A1FFAR1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL2319627 | 0.79 | ALDH1A1 (0.46) | TSHRALDH1A1NLRP3MEN1KMT2A | |
| SCHEMBL27544216 | 0.77 | ALDH1A1 (0.47) | TSHRALDH1A1FFAR1NLRP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790260-B1 | Solid catalyst components for polymerization | JAPAN POLYOLEFINS CO LTD (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-5902765-A | MADE BY REACTING A MAGNESIUM DIHALIDE WITH TETRAHYDROFURAN, BUTYL ETHER OR DIETHYL ETHER AND TREATING THE SOLID SUBSTANCE WITH AN ELECTRON DONATIVE COMPOUND HAVING TWO OR MORE ALKOXY OR ESTER GROUPS, CONTACTING WITH TITANIUM; STEREOREGULARITY | JAPAN POLYOLEFINS CO., LTD. (JP) | 1999-05-11 | — | — | US | disclosed |
| EP-0790260-A1 | Solid catalyst components for polymerization | JAPAN POLYOLEFINS CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |