Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071540 | 0.84 | TAAR1 (0.32) | HPGDTSHRMAPTTAAR1CBFB | |
| SCHEMBL21196227 | 0.79 | HPGD (0.32) | HPGDHSD17B10CYP3A4TSHRHSP90AA1 | |
| SCHEMBL7636439 | 0.78 | TAAR1 (0.35) | HPGDHSD17B10CYP3A4TSHRHSP90AA1 | |
| SCHEMBL11334164 | 0.76 | TAAR1 (0.32) | TAAR1NR4A2 | |
| SCHEMBL5706655 | 0.76 | TAAR1 (0.32) | TAAR1 | |
| SCHEMBL23409459 | 0.72 | TAAR1 (0.33) | HSD17B10CYP3A4ADRA2AADRA2CADRA1A | |
| SCHEMBL29971157 | 0.72 | TAAR1 (0.33) | HSD17B10CYP3A4ADRA2AADRA2CADRA1A | |
| SCHEMBL3082888 | 0.72 | TSHR (0.35) | HPGDHSD17B10CYP3A4TSHRERBB2 | |
| SCHEMBL364805 | 0.72 | CA1 (0.36) | TAAR1CBFB | |
| SCHEMBL29756095 | 0.72 | CA1 (0.36) | TAAR1CBFB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6452056-B1 | REDUCING FLUORINATED BENZONITRILE TO A BENZYLAMINE WHICH IS REPLACED WITH A HYDROXYL GROUP | ASAHI GLASS COMPANY, LIMITED (JP) | 2002-09-17 | — | — | US | disclosed |
| EP-1114809-A1 | PROCESS FOR THE PREPARATION OF FLUOROBENZYL DERIVATIVES | Asahi Glass Co., Ltd. (JP) | 2001-07-11 | — | — | EP | disclosed |