SCHEMBL23409459

SCHEMBL23409459

OCc1c(F)cc(O)c(F)c1Cl

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.33
DAO P14920 1/20 0.32
ADRB2 P07550 1/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29971157 1.00 TAAR1 (0.33) TAAR1DAOADRB2CYP3A4HSD17B10
SCHEMBL23409587 0.83 HSD17B10 (0.38) CYP3A4HSD17B10ADRA2AADRA2CADRA1A
SCHEMBL29970962 0.83 HSD17B10 (0.38) CYP3A4HSD17B10ADRA2AADRA2CADRA1A
SCHEMBL22437279 0.80 TAAR1 (0.37) TAAR1ADRB2CYP3A4HSD17B10ADRA2A
SCHEMBL23409597 0.80 ALDH1A1 (0.36) CYP3A4HSD17B10ADRA1A
SCHEMBL23409499 0.80 DRD4 (0.30)
SCHEMBL29970456 0.80 ALDH1A1 (0.36) CYP3A4HSD17B10ADRA1A
SCHEMBL29969345 0.80 DRD4 (0.30)
SCHEMBL7629009 0.72 HPGD (0.34) TAAR1CYP3A4HSD17B10ADRA2AADRA2C
SCHEMBL3082888 0.70 TSHR (0.35) TAAR1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12466781-B2 Thyromimetics AUTOBAHN THERAPEUTICS, INC. (US) 2025-11-11 US disclosed
US-20230048992-A1 NOVEL THYROMIMETICS AUTOBAHN THERAPEUTICS, INC. 2023-02-16 US disclosed
US-20230048992-A1 NOVEL THYROMIMETICS AUTOBAHN THERAPEUTICS, INC. 2023-02-16 US disclosed
CN-115279359-A Novel thyromimetic agents 速通医疗公司 2022-11-01 CN disclosed
EP-4065098-A1 NOVEL THYROMIMETICS Autobahn Therapeutics, Inc. (US) 2022-10-05 EP disclosed
WO-2021108549-A1 NOVEL THYROMIMETICS AUTOBAHN THERAPEUTICS, INC. (US) 2021-06-03 WO disclosed
WO-2021108549-A1 NOVEL THYROMIMETICS AUTOBAHN THERAPEUTICS, INC. (US) 2021-06-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230048992-A1 NOVEL THYROMIMETICS TSHR, TPO, CHRM1 TAAR1 13/4885DAO 1719/4885ADRB2 43/4885
US-12466781-B2 Thyromimetics TPO, TSHR, CHRM1 TAAR1 14/4885DAO 1668/4885ADRB2 51/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.