Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 4/20 | 0.56 |
| ▸ | ESR2 known ✓ | Q92731 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28563070 | 1.00 | CYP3A4 (0.67) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL28985507 | 1.00 | CYP3A4 (0.67) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL158139 | 1.00 | CYP3A4 (0.67) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL6135660 | 1.00 | CYP3A4 (0.67) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL8050008 | 1.00 | CYP3A4 (0.67) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL1076750 | 0.97 | CYP3A4 (0.63) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL3889924 | 0.97 | CYP3A4 (0.63) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL8926679 | 0.97 | CYP3A4 (0.63) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL9816160 | 0.97 | CYP3A4 (0.63) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL8682342 | 0.97 | CYP3A4 (0.63) | CYP3A4TDP1ESR1ESR2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329021-B1 | Preparation of advanced epoxy resins and dihydric phenols in the presence of phosphonium compounds | DOW CHEMICAL CO (US) | 1994-01-26 | — | — | EP | claimed |
| EP-0329021-A2 | Preparation of advanced epoxy resins and dihydric phenols in the presence of phosphonium compounds | THE DOW CHEMICAL COMPANY (US) | 1989-08-23 | — | — | EP | claimed |
| CN-104903320-B | Nitrogen-containing heterocycle compound or its salt | 富士胶片株式会社 | 2018-11-13 | — | — | CN | disclosed |
| CN-107922555-A | Curing composition | 东亚合成株式会社 | 2018-04-17 | — | — | CN | disclosed |
| CN-100491445-C | Powder coating matting agents comprising esteramide condensation products | GRACE GMBH & CO KG (DE) | 2009-05-27 | — | — | CN | disclosed |
| CN-1671771-A | Powder coating matting agent comprising ester amide condensation product | GRACE GMBH & CO KG (DE) | 2005-09-21 | — | — | CN | disclosed |
| EP-0780452-B1 | Aqueous paint | TOYO SEIKAN KAISHA LTD (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-5763507-A | EPOXY ACRYLATE RESIN | TOYO SEIKAN KAISHA, LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0780452-A2 | Aqueous paint | TOYO SEIKAN KAISHA LIMITED (JP) | 1997-06-25 | — | — | EP | disclosed |
| US-5591788-A | Cationic, advanced epoxy resin compositions incorporating glycidyl ethers of oxyalkylated aromatic or cycloaliphatic diols | THE DOW CHEMICAL COMPANY (US) | 1997-01-07 | — | — | US | disclosed |
| US-5360838-A | Catalytic reaction with nucleophile and epoxy resin | THE DOW CHEMICAL COMPANY (US) | 1994-11-01 | — | — | US | disclosed |
| EP-0209572-A4 | EPOXY NOVOLAC RESINS HAVING REDUCED 2-FUNCTIONAL COMPONENTS AND A PROCESS FOR REDUCING 2-FUNCTIONAL COMPONENTS IN NOVOLAC RESINS. | DOW CHEMICAL CO (US) | 1988-10-24 | — | — | EP | disclosed |
| CN-87104910-A | Cationic improved epoxy resin compositions | — | 1988-05-04 | — | — | CN | disclosed |
| WO-1988000604-A1 | CONTROLLED FILM BUILD CATHODIC ELECTRODEPOSITION EPOXY COATINGS | THE DOW CHEMICAL COMPANY (US) | 1988-01-28 | — | — | WO | disclosed |
| EP-0253404-A2 | Controlled film build epoxy coatings applied by cathodic electrodeposition | THE DOW CHEMICAL COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |
| US-4708996-A | Stable dispersions of polymers in polyepoxides | THE DOW CHEMICAL COMPANY (US) | 1987-11-24 | — | — | US | disclosed |
| EP-0209572-A1 | EPOXY NOVOLAC RESINS HAVING REDUCED 2-FUNCTIONAL COMPONENTS AND A PROCESS FOR REDUCING 2-FUNCTIONAL COMPONENTS IN NOVOLAC RESINS | THE DOW CHEMICAL COMPANY (US) | 1987-01-28 | — | — | EP | disclosed |
| EP-0189474-A1 | A PROCESS FOR THE PREPARATION OF EPOXY RESINS OF CONTROLLED CONVERTION. | DOW CHEMICAL CO (US) | 1986-08-06 | — | — | EP | disclosed |
| WO-1986004075-A1 | EPOXY NOVOLAC RESINS HAVING REDUCED 2-FUNCTIONAL COMPONENTS AND A PROCESS FOR REDUCING 2-FUNCTIONAL COMPONENTS IN NOVOLAC RESINS | THE DOW CHEMICAL COMPANY (US) | 1986-07-17 | — | — | WO | disclosed |
| WO-1986001216-A1 | EPOXY RESINS OF CONTROLLED CONVERSION AND A PROCESS FOR THEIR PREPARATION | THE DOW CHEMICAL COMPANY (US) | 1986-02-27 | — | — | WO | disclosed |