Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 4/20 | 0.56 |
| ▸ | ESR2 known ✓ | Q92731 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28563070 | 1.00 | CYP3A4 (0.67) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL28985507 | 1.00 | CYP3A4 (0.67) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL158139 | 1.00 | CYP3A4 (0.67) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL6135660 | 1.00 | CYP3A4 (0.67) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL7629010 | 1.00 | CYP3A4 (0.67) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL1076750 | 0.97 | CYP3A4 (0.63) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL3889924 | 0.97 | CYP3A4 (0.63) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL8926679 | 0.97 | CYP3A4 (0.63) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL9816160 | 0.97 | CYP3A4 (0.63) | CYP3A4TDP1ESR1ESR2CES2 | |
| Acetic Acid SCHEMBL8682342 | 0.97 | CYP3A4 (0.63) | CYP3A4TDP1ESR1ESR2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063151-B | High-adhesion-performance flexible epoxy tile adhesive and preparation method thereof | 广州市连拓新材料有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-118063837-B | Preparation process of polyurethane foam material with flame retardant function | 广州帕卡汽车零部件有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118063151-A | High-adhesion-performance flexible epoxy tile adhesive and preparation method thereof | 广州市连拓新材料有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-118063837-A | Preparation process of polyurethane foam material with flame retardant function | 广州帕卡汽车零部件有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-113458046-B | Preparation method of stretch-proofing rubber for air cushion ship | 德清县强业舰船装备有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-113736040-A | Acrylic acid modified epoxy resin and preparation method and application thereof | 苏州艾迪亨斯新材料科技有限公司 | 2021-12-03 | — | — | CN | claimed |
| CN-113458046-A | Anti-tensile rubber production equipment for air cushion ship and preparation method thereof | 德清县强业舰船装备有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-118063151-B | High-adhesion-performance flexible epoxy tile adhesive and preparation method thereof | 广州市连拓新材料有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118251395-A | Esatitecan derivatives and antibody-drug conjugates thereof | ALX肿瘤学股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-118063151-A | High-adhesion-performance flexible epoxy tile adhesive and preparation method thereof | 广州市连拓新材料有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-117777830-A | UV (ultraviolet) coating for vacuum coating of plastic flat plate as well as preparation and application thereof | 温州职业技术学院 | 2024-03-29 | — | — | CN | disclosed |
| CN-113736040-B | Acrylic acid modified epoxy resin and preparation method and application thereof | 苏州艾迪亨斯新材料科技有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-111285878-B | Diazepine compound, preparation method thereof, and pharmaceutical salt, prodrug and application thereof | 杭州新博思生物医药有限公司 | 2022-05-13 | — | — | CN | disclosed |
| EP-0347939-A1 | Method for preparing alpha-(4-isobutylphenyl) propionic acid or its precursor | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |
| US-4889952-A | (Phenylethenyl) phenylpropionaldehyde and method for producing (benzolyphenyl) propionic acid using the same | NIPPON PETROCHEMICAL COMPANY, LTD. (JP) | 1989-12-26 | — | — | US | disclosed |
| US-4870069-A | POST-COITAL FERTILITY CONTROL | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-09-26 | — | — | US | disclosed |
| EP-0311689-A1 | PROCESS FOR SELECTIVELY MONOHYDROFORMYLATING DIOLEFIN | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1989-04-19 | — | — | EP | disclosed |
| EP-0306538-A1 | PROCESS FOR PREPARING ALPHA-(3-BENZYLPHENYL)PROPIONIC ACID DERIVATIVE | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1989-03-15 | — | — | EP | disclosed |
| EP-0283038-A1 | (Vinylphenyl)phenylmethane and method for producing (benzoylphenyl)propionic acid | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1988-09-21 | — | — | EP | disclosed |
| EP-0282066-A2 | (Phenylethenyl) phenylpropionaldehyde and method for producing (benzoylphenyl) propionic acid using the same | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1988-09-14 | — | — | EP | disclosed |