Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512628 | 0.88 | KDM4E (0.54) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL6502302 | 0.86 | KDM4E (0.58) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL6506713 | 0.84 | TSHR (0.56) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL6503378 | 0.84 | TSHR (0.56) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL6503320 | 0.84 | TSHR (0.56) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL6501752 | 0.84 | TSHR (0.56) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL15673079 | 0.78 | CA2 (0.30) | CA2CA9 | |
| SCHEMBL27313635 | 0.76 | TSHR (0.41) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL11006176 | 0.75 | KDM4E (0.43) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL11006179 | 0.75 | KDM4E (0.43) | USP2TSHRKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712395-B1 | PROCESS FOR THE PREPARATION OF FLUOROALKENYLTHIO HETEROCYCLIC DERIVATIVES | SYNGENTA LTD (GB) | 2002-05-22 | — | — | EP | disclosed |
| US-5914423-A | 4-BROMO-3,4,4-TRIFLUOROBUTYL (ALKYL OR ALKYLPHENYL) SULFONATES; PREPARING 4-BROMO-1,1-DIFLUORO-BUT-1-ENE BY DEBROMOFLUORINATION OF 1,4-DIBROMO-1,1,2-TRIFLUOROBUTANE; CHEMICAL INTERMEDIATES TO NEMATICIDE PRODUCTION | ZENECA, LIMITED (GB) | 1999-06-22 | — | — | US | disclosed |
| US-5728833-A | REACTING MERCAPTO-SUBSTITUTED HETEROCYCLIC COMPOUND WITH 4-HALO-1,1-DIFLUOROBUT-1-ENE OR 4,4-DIFLUOROBUT-3-ENYL SULFONATE | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |