Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127127 | 0.87 | NPC1 (0.53) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL6886097 | 0.83 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL7633538 | 0.82 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL5510171 | 0.82 | TSHR (0.50) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL7628642 | 0.80 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL13355960 | 0.80 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2AESR1 | |
| Toluic Acid SCHEMBL2528475 | 0.80 | ALDH1A1 (0.52) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL7632492 | 0.79 | KMT2A (0.44) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL29436920 | 0.79 | NPC1 (0.53) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL777261 | 0.79 | NPC1 (0.53) | NPC1RAB9AMEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233014-A1 | ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME | NOF CORPORATION (JP) | 2002-08-21 | — | — | EP | disclosed |