Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23830115 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP3A4MAOBTP53MAPT | |
| SCHEMBL10355875 | 0.76 | ALDH1A1 (0.42) | ALDH1A1CYP3A4MAOBMAPTPOLB | |
| SCHEMBL1270081 | 0.74 | MAOB (0.46) | ALDH1A1CYP3A4MAOBTP53MAPT | |
| SCHEMBL7629801 | 0.73 | CYP3A4 (0.42) | ALDH1A1CYP3A4MAOBTP53MAPT | |
| SCHEMBL1119437 | 0.70 | MAOB (0.41) | ALDH1A1CYP3A4MAOBTP53MAPT | |
| SCHEMBL30107929 | 0.68 | MAOB (0.86) | ALDH1A1CYP3A4MAOBTP53MAPT | |
| SCHEMBL7747934 | 0.68 | ALDH1A1 (0.65) | ALDH1A1CYP3A4MAOBTP53MAPT | |
| SCHEMBL55303 | 0.68 | MAOB (0.86) | ALDH1A1CYP3A4MAOBTP53MAPT | |
| SCHEMBL29414092 | 0.68 | MAOB (0.86) | ALDH1A1CYP3A4MAOBTP53MAPT | |
| SCHEMBL4455312 | 0.66 | MAOB (0.82) | ALDH1A1CYP3A4MAOBTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458912-B1 | 1,3-BIS(4-AMINOPHENOXY)BENZENE REPRESENTED BY THE CHEMICAL FORMULA (3) FOR PRODUCTION OF THE ABOVE POLYIMIDE, CHARACTERIZED IN THAT THE CONTENT OF AN AZO COMPOUND IS FROM 0.0 TO 0.2%. THE THERMOPLASTIC POLYIMIDE OF THE PRESENT | MITSUI CHEMICALS, INC. (JP) | 2002-10-01 | — | — | US | disclosed |
| EP-1090945-A1 | CRYSTALLINE POLYIMIDE FOR MELT MOLDING WITH SATISFACTORY THERMAL STABILITY | Mitsui Chemicals, Inc. (JP) | 2001-04-11 | — | — | EP | disclosed |