SCHEMBL7629843

SCHEMBL7629843

CCCCCc1ccc(C(=O)OO[C]2CCCC2)cc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 0.50
THRA P10827 10/20 0.49
THRB P10828 10/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
ALDH1A1 P00352 2/20 0.49
RARA P10276 1/20 0.49
MAPT P10636 1/20 0.49
MTOR P42345 1/20 0.49
PLA2G1B P04054 1/20 0.47
ATG4B Q9Y4P1 1/20 0.47
CYP4F2 P78329 1/20 0.47
CYP4A11 Q02928 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7632788 0.99 THRA (0.51) RARBTHRATHRBMEN1KMT2A
SCHEMBL7627135 0.99 RARB (0.49) RARBTHRATHRBMEN1KMT2A
SCHEMBL7633401 0.99 RARB (0.49) RARBTHRATHRBMEN1KMT2A
SCHEMBL7631325 0.97 THRA (0.50) RARBTHRATHRBMEN1KMT2A
SCHEMBL7635197 0.97 THRA (0.50) RARBTHRATHRBMEN1KMT2A
SCHEMBL7636996 0.96 RARB (0.49) RARBTHRATHRBMEN1KMT2A
SCHEMBL7625103 0.94 RARB (0.48) RARBTHRATHRBMEN1KMT2A
SCHEMBL7630924 0.94 RARB (0.48) RARBTHRATHRBMEN1KMT2A
SCHEMBL7634284 0.90 PLK1 (0.46) THRBKMT2AALDH1A1MAPTPLA2G1B
SCHEMBL7633321 0.89 RARB (0.50) RARBTHRATHRBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed