SCHEMBL7629937

SCHEMBL7629937

CO[Si](OC)(OC)c1ccc(S(=O)(=O)N=[N+]=[N-])cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 9/20 0.33
PRSS1 P07477 9/20 0.33
PRSS2 P07478 9/20 0.33
PRSS3 P35030 9/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA5A P35218 1/20 0.33
CA9 Q16790 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
BCL2L1 Q07817 1/20 0.31
BAK1 Q16611 1/20 0.31
PKM P14618 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7622409 0.87 F2 (0.32) F2PRSS1PRSS2PRSS3CA1
SCHEMBL7869254 0.83 F2 (0.35) F2PRSS1PRSS2PRSS3
SCHEMBL7630010 0.82 BCL2L1 (0.30) CA1CA2CA5ACA9CA5B
SCHEMBL10823807 0.81 CA1 (0.43) F2PRSS1PRSS2PRSS3CA1
SCHEMBL11122850 0.80
SCHEMBL7628196 0.80 CA1 (0.33) CA1CA2CA5ACA9CA5B
SCHEMBL11122852 0.79 BCL2L1 (0.31) BCL2L1BAK1
SCHEMBL1683275 0.79 F2 (0.54) F2PRSS1PRSS2PRSS3CA1
SCHEMBL7877837 0.77 TSHR (0.38) CA1CA2CA5ACA9CA5B
SCHEMBL7878015 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1218422-A1 AZIDOSILANE-MODIFIED, MOISTURE-CURABLE POLYOLEFIN POLYMERS, PROCESS FOR MAKING, AND ARTICLES OBTAINED THEREFROM THE DOW CHEMICAL COMPANY (US) 2002-07-03 EP disclosed
US-6331597-B1 Azidosilane-modified, moisture-curable polyolefin polymers, process for making, and articles obtained therefrom THE DOW CHEMICAL COMPANY 2001-12-18 US disclosed
WO-2001010914-A1 AZIDOSILANE-MODIFIED, MOISTURE-CURABLE POLYOLEFIN POLYMERS, PROCESS FOR MAKING, AND ARTICLES OBTAINED THEREFROM THE DOW CHEMICAL COMPANY (US) 2001-02-15 WO disclosed
EP-0150774-B1 WATER CURABLE, AZIDE SULFONYL SILANE MODIFIED, ALKYLENE ACRYLATE COPOLYMERS UNION CARBIDE CORPORATION (US) 1989-05-03 EP disclosed
EP-0150773-B1 WATER CURABLE, AZIDE SULFONYL SILANE MODIFIED ETHYLENE POLYMERS UNION CARBIDE CORPORATION (US) 1989-05-03 EP disclosed
EP-0119011-B1 ADHESIVE PROCESS HERCULES INCORPORATED (US) 1987-11-04 EP disclosed
US-4551504-A DIELECTRICS UNION CARBIDE CORPORATION (US) 1985-11-05 US disclosed
EP-0150773-A2 Water curable, azide sulfonyl silane modified ethylene polymers UNION CARBIDE CORPORATION (US) 1985-08-07 EP disclosed
EP-0150774-A2 Water curable, azide sulfonyl silane modified, alkylene acrylate copolymers UNION CARBIDE CORPORATION (US) 1985-08-07 EP disclosed
US-4514545-A INSULATION OR JACKETS FOR UNDERGROUND WIRES AND CABLES, IMPROVED E UNION CARBIDE CORPORATION (US) 1985-04-30 US disclosed
US-4447495-A AN AZIDOSILANE COUPLING AGENT FOR ADHEARING POLYMER AND SILICEOUS MATERIAL HERCULES, INCORPORATED (US) 1984-05-08 US disclosed