Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7628196 | 0.92 | CA1 (0.33) | TSHRCA1CA2CA9CA12 | |
| SCHEMBL7622816 | 0.89 | TSHR (0.36) | TSHRCA1CA2CA9CA12 | |
| SCHEMBL7869260 | 0.86 | ABCB1 (0.33) | TSHRCA1CA2CA9CA12 | |
| SCHEMBL7630010 | 0.85 | BCL2L1 (0.30) | CA1CA2CA9CA12CA7 | |
| SCHEMBL7878030 | 0.81 | CA1 (0.32) | CA1CA2CA9CA12CA7 | |
| SCHEMBL7628576 | 0.77 | — | — | |
| SCHEMBL7629937 | 0.77 | F2 (0.33) | CA1CA2CA9CYP1A2CYP3A4 | |
| SCHEMBL7878015 | 0.77 | — | — | |
| SCHEMBL7877836 | 0.77 | ABCB1 (0.34) | TSHRCA1CA2CA9CA12 | |
| SCHEMBL14798777 | 0.77 | CA2 (0.40) | TSHRCA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331597-B1 | Azidosilane-modified, moisture-curable polyolefin polymers, process for making, and articles obtained therefrom | THE DOW CHEMICAL COMPANY | 2001-12-18 | — | — | US | disclosed |