SCHEMBL7630007

SCHEMBL7630007

Oc1ccc(Cn2nccn2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.61
ESR1 P03372 5/20 0.44
ESR2 Q92731 3/20 0.44
MET P08581 1/20 0.42
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
ABAT P80404 1/20 0.41
CA2 P00918 1/20 0.39
ALDH1A1 P00352 2/20 0.39
BLM P54132 2/20 0.39
CYP1A2 P05177 1/20 0.39
POLB P06746 1/20 0.39
CYP3A4 P08684 1/20 0.39
DBH P09172 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
NFKB1 P19838 1/20 0.39
KDM4E B2RXH2 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17610794 0.77 CYP19A1 (0.61) CYP19A1ALDH1A1POLBKDM4EIDO1
SCHEMBL1582393 0.77 CYP19A1 (0.61) CYP19A1ALDH1A1KDM4ETAAR1IDO1
SCHEMBL10194247 0.77 CYP19A1 (0.61) CYP19A1ALDH1A1CYP1A2POLBCYP3A4
SCHEMBL3142438 0.77 CYP19A1 (0.61) CYP19A1ALDH1A1CYP3A4TSHRKDM4E
SCHEMBL28791596 0.76 CYP19A1 (0.67) CYP19A1ALDH1A1CYP1A2CYP3A4HPGD
SCHEMBL5049285 0.72 IDO1 (0.39) CYP19A1ESR1ESR2METHSP90AB1
SCHEMBL7627846 0.72 MAPT (0.62) CYP19A1CA2HPGDTSHRKDM4E
SCHEMBL1264013 0.72 ESR1 (0.44) CYP19A1ESR1ESR2ALDH1A1HPGD
SCHEMBL13903594 0.72 CYP19A1 (0.55) CYP19A1CA2ALDH1A1CYP1A2CYP3A4
SCHEMBL12340306 0.70 KDM4E (0.68) CYP19A1ESR1ESR2ABATALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0754683-B1 ETHER COMPOUND, USE THEREOF, AND INTERMEDIATE FOR PRODUCING THE COMPOUND SUMITOMO CHEMICAL CO (JP) 2002-08-14 EP disclosed
CN-1079794-C Ether compound, use thereof, and intermediate for producing the compound SUMITOMO CHEM IND (JP) 2002-02-27 CN disclosed
US-5684022-A ANTIFERTILITY AGENT PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-11-04 US disclosed
CN-1149289-A Ether compounds, their use and intermediates for their preparation SUMITOMO CHEMICAL CO (JP) 1997-05-07 CN disclosed
EP-0754683-A1 ETHER COMPOUND, USE THEREOF, AND INTERMEDIATE FOR PRODUCING THE COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-01-22 EP disclosed