Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | PDE6D | O43924 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304768 | 0.83 | CYP19A1 (0.58) | KMT2AMEN1CYP19A1ALDH1A1KDM4E | |
| SCHEMBL22001014 | 0.80 | TP53 (0.57) | KMT2AMEN1ALDH1A1KDM4ENPC1 | |
| SCHEMBL4834224 | 0.80 | TNF (0.44) | KMT2ACYP19A1ALDH1A1KDM4ENPC1 | |
| SCHEMBL9304572 | 0.80 | RAB9A (0.51) | KMT2AMEN1CYP19A1ALDH1A1KDM4E | |
| SCHEMBL29234887 | 0.79 | CXCR2 (0.47) | KMT2AALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL28861008 | 0.76 | HSP90AA1 (0.49) | ESR1ESR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL5846689 | 0.74 | TAAR1 (0.39) | ESR1ESR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL29072079 | 0.74 | ALOX5 (0.47) | ALDH1A1KDM4EGLAGAAMAPT | |
| SCHEMBL8745426 | 0.73 | KDM4E (0.42) | CYP19A1ALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL15569205 | 0.73 | ALDH1A1 (0.72) | ESR1ALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120329885-A1 | Ultraviolet light absorbing compounds based on benzyl substituted 2-(2- hydroxyphenyl) benzotriazoles | CHANG CHIA-HU (US) | 2012-12-27 | — | — | US | disclosed |
| US-8163934-B2 | Ultraviolet light absorbing ketones of 2-(2-hydroxyphenyl) benzotriazole | CHANG CHIA-HU (US) | 2012-04-24 | — | — | US | disclosed |
| EP-2332013-A1 | ULTRAVIOLET LIGHT ABSORBING KETONES OF 2-(2-HYDROXYPHENYL) BENZOTRIAZOLE | Chang, Chia-Hu (US) | 2011-06-15 | — | — | EP | disclosed |
| US-20110038816-A1 | Ultraviolet light absorbing ketones of 2-(2-hydroxyhenyl) benzotriazole | CHANG CHIA-HU | 2011-02-17 | — | — | US | disclosed |
| US-7847103-B2 | Ultraviolet light absorbing ketones of 2-(2-hydroxyphenyl) benzotriazole | CHANG CHIA-HU | 2010-12-07 | — | — | US | disclosed |
| US-20100086500-A1 | Ultraviolet light absorbing ketones of 2-(2-Hydroxyphenyl) benzotriazole | CHANG CHIA-HU | 2010-04-08 | — | — | US | disclosed |
| WO-2010039229-A1 | ULTRAVIOLET LIGHT ABSORBING KETONES OF 2-(2-HYDROXYPHENYL) BENZOTRIAZOLE | CHANG CHIA-HU (US) | 2010-04-08 | — | — | WO | disclosed |
| EP-1077246-B1 | Use of benzotriazolyl-alkylene bisphenol compounds as antioxidants for organic materials | JOHOKU CHEMICAL CO LTD (JP) | 2005-01-26 | — | — | EP | disclosed |
| EP-0847997-B1 | Process for the preparation of Benzotriazolylalkylene bisphenol compounds | JOHOKU CHEMICAL CO LTD (JP) | 2002-02-06 | — | — | EP | disclosed |
| EP-1077246-A2 | Use of benzotriazolyl-alkylene bisphenol compounds as antioxidants for organic materials | Johoku Chemical Co., Ltd. (JP) | 2001-02-21 | — | — | EP | disclosed |
| US-5932142-A | REACTING 2-HYDROXYPHENYLBENZOTRIAZOLE AND 2,4-DISUBSTITUTED PHENOL WITH AN ALDEHYDE | JOHOKU CHEMICAL CO., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0847997-A1 | Benzotriazolyl-alkylene bisphenol compounds, process for their preparation, and stabilized organic materials containing them | Johoku Chemical Co., Ltd. (JP) | 1998-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110038816-A1 | Ultraviolet light absorbing ketones of 2-(2-hydroxyhenyl) benzotriazole | HCRTR2, HCRTR1, POLL | ESR1 1842/4885ESR2 1110/4885KMT2A 345/4885 |
| US-20120329885-A1 | Ultraviolet light absorbing compounds based on benzyl substituted 2-(2- hydroxyphenyl) benzotriazoles | AHR, ARNT, BCAT1 | ESR1 838/4885ESR2 385/4885KMT2A 1132/4885 |
| US-20100086500-A1 | Ultraviolet light absorbing ketones of 2-(2-Hydroxyphenyl) benzotriazole | HCRTR2, HCRTR1, PAH | ESR1 1928/4885ESR2 1175/4885KMT2A 357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.