Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.56 |
| ▸ | PPARG | P37231 | 12/20 | 0.49 |
| ▸ | PPARD | Q03181 | 4/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | PTPRF | P10586 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL543191 | 1.00 | PPARA (0.56) | PPARAPPARGPPARDSLC7A5PTPRF | |
| SCHEMBL7108636 | 0.91 | PPARA (0.57) | PPARAPPARGPPARDSLC7A5PTPRF | |
| SCHEMBL7103261 | 0.91 | PPARA (0.57) | PPARAPPARGPPARDSLC7A5PTPRF | |
| SCHEMBL5607507 | 0.91 | PPARA (0.57) | PPARAPPARGPPARDSLC7A5PTPRF | |
| SCHEMBL7102287 | 0.88 | PPARA (0.51) | PPARAPPARGPPARDSLC7A5PTPRF | |
| SCHEMBL7102284 | 0.88 | PPARA (0.51) | PPARAPPARGPPARDSLC7A5PTPRF | |
| SCHEMBL6500458 | 0.88 | PPARA (0.51) | PPARAPPARGPPARDSLC7A5PTPRF | |
| SCHEMBL543815 | 0.87 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL5543269 | 0.87 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL3233074 | 0.87 | PPARA (0.72) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254101-A1 | PROPIONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF DIABETES AND OBESITY | Novo Nordisk A/S (DK) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055085-A1 | PROPIONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF DIABETES AND OBESITY | NOVO NORDISK A/S (DK) | 2001-08-02 | — | — | WO | disclosed |