Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500458 | 1.00 | PPARA (0.51) | PPARAPPARGPPARDNR5A1ESR1 | |
| SCHEMBL7102287 | 1.00 | PPARA (0.51) | PPARAPPARGPPARDNR5A1ESR1 | |
| SCHEMBL5607507 | 0.94 | PPARA (0.57) | PPARAPPARGPPARDESR1LMNA | |
| SCHEMBL7103261 | 0.94 | PPARA (0.57) | PPARAPPARGPPARDESR1LMNA | |
| SCHEMBL7108636 | 0.94 | PPARA (0.57) | PPARAPPARGPPARDESR1LMNA | |
| SCHEMBL4041857 | 0.88 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL10697327 | 0.88 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL8084774 | 0.88 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL7630188 | 0.88 | PPARA (0.56) | PPARAPPARGPPARDESR1SLC6A2 | |
| SCHEMBL543191 | 0.88 | PPARA (0.56) | PPARAPPARGPPARDESR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030008361-A1 | Process for the preparation of substituted 3-phenyl-propanoic acid esters and substituted 3-phenyl-propanoic acids | EBDRUP SOREN (DK) | 2003-01-09 | — | — | US | disclosed |
| EP-1206565-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-PHENYL-PROPANOIC ACID ESTERS AND SUBSTITUTED 3-PHENYL-PROPANOIC ACIDS | NOVO NORDISK A/S (DK) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001011073-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-PHENYL-PROPANOIC ACID ESTERS AND SUBSTITUTED 3-PHENYL-PROPANOIC ACIDS | NOVO NORDISK A/S (DK) | 2001-02-15 | — | — | WO | disclosed |