Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RXRA | P19793 | 2/20 | 0.49 |
| ▸ | RXRB | P28702 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30929954 | 0.86 | MRGPRX4 (0.62) | MRGPRX4MEN1KMT2AHPGDRXRA | |
| SCHEMBL9341996 | 0.86 | MRGPRX4 (0.57) | MRGPRX4MEN1KMT2APTGER1HPGD | |
| SCHEMBL30929959 | 0.84 | RXRA (0.57) | NR4A2NR4A1NR4A3MRGPRX4MEN1 | |
| SCHEMBL29506850 | 0.84 | RXRA (0.57) | NR4A2NR4A1NR4A3MRGPRX4MEN1 | |
| SCHEMBL30929962 | 0.84 | MRGPRX4 (0.60) | MRGPRX4MEN1KMT2AHPGDRXRA | |
| SCHEMBL30929983 | 0.84 | MRGPRX4 (0.78) | NR4A2MRGPRX4MEN1KMT2AHPGD | |
| SCHEMBL5921632 | 0.81 | MRGPRX4 (0.76) | NR4A2NR4A1NR4A3MRGPRX4MEN1 | |
| SCHEMBL5695710 | 0.81 | NR4A2 (0.59) | NR4A2NR4A1NR4A3MRGPRX4MEN1 | |
| SCHEMBL1600077 | 0.81 | MRGPRX4 (0.62) | NR4A2NR4A1NR4A3MRGPRX4MEN1 | |
| SCHEMBL29556736 | 0.81 | MRGPRX4 (0.62) | NR4A2NR4A1NR4A3MRGPRX4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938488-B1 | PHOSPHINE LIGANDS | OXFORD ASYMMETRY INTERNAT PLC (GB) | 2002-01-02 | — | — | EP | disclosed |
| US-6162951-A | Phosphine ligands | OXFORD ASYMMETRY INTERNATIONAL PLC (GB) | 2000-12-19 | — | — | US | disclosed |