Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7630550 | 1.00 | PPIB (0.44) | PPIBKDM4EKLK7MALT1HTR2A | |
| SCHEMBL7630543 | 1.00 | PPIB (0.44) | PPIBKDM4EKLK7MALT1HTR2A | |
| SCHEMBL31562962 | 0.78 | ALDH1A1 (0.40) | KDM4EMALT1HTR2AHTR2CHTR2B | |
| SCHEMBL10645197 | 0.70 | PPIB (0.45) | PPIBKDM4EKLK7HTR2AHTR2C | |
| SCHEMBL9965929 | 0.68 | HDAC3 (0.58) | PPIBKDM4EKLK7HTR2CALDH1A1 | |
| SCHEMBL6086511 | 0.68 | KDM4E (0.65) | PPIBKDM4EKLK7ALDH1A1GAA | |
| SCHEMBL620146 | 0.68 | KDM4E (0.63) | PPIBKDM4EKLK7ALDH1A1GAA | |
| SCHEMBL12490443 | 0.68 | PPIB (0.43) | PPIBKDM4EKLK7MALT1ALDH1A1 | |
| SCHEMBL9744849 | 0.68 | PARP1 (0.46) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL8515318 | 0.68 | PPIB (0.43) | PPIBKDM4EKLK7MALT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891365-B1 | BENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSES | UNIV CALIFORNIA (US) | 2002-10-16 | — | — | EP | disclosed |
| EP-0891365-A1 | BENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036907-A9 | BENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE | — | 1997-12-04 | — | — | WO | disclosed |
| WO-1997036907-A1 | BENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-10-09 | — | — | WO | disclosed |