Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7630897 | 1.00 | HDAC8 (0.43) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL7631423 | 1.00 | HDAC8 (0.43) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL7633414 | 1.00 | HDAC8 (0.43) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL7628781 | 1.00 | HDAC8 (0.43) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL7631609 | 1.00 | HDAC8 (0.43) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL7631928 | 0.99 | PARP1 (0.41) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL7627807 | 0.96 | PARP1 (0.44) | HDAC8HDAC6PARP1CTNNB1WNT3A | |
| SCHEMBL7628461 | 0.89 | PARP1 (0.45) | HDAC8HDAC6PARP1CTNNB1WNT3A | |
| SCHEMBL7633001 | 0.84 | HDAC3 (0.37) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL7633394 | 0.84 | CES2 (0.48) | HDAC6HDAC1PARP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233014-A1 | ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME | NOF CORPORATION (JP) | 2002-08-21 | — | — | EP | disclosed |