SCHEMBL7630845

SCHEMBL7630845

[c]1ccc(CC=NOCc2ccccc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
IDO1 P14902 1/20 0.38
AGXT P21549 1/20 0.37
TSHR P16473 2/20 0.36
MAOB P27338 1/20 0.36
ALDH1A1 P00352 3/20 0.35
HPGD P15428 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
RET P07949 1/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7966098 0.89 IDO1 (0.46) NPC1RAB9ASMN1; SMN2GAAKMT2A
SCHEMBL10691482 0.89 IDO1 (0.46) NPC1RAB9ASMN1; SMN2GAAKMT2A
SCHEMBL7623616 0.84 NPC1 (0.39) NPC1RAB9ASMN1; SMN2GAAKMT2A
SCHEMBL5958238 0.78 NPC1 (0.60) NPC1RAB9ASMN1; SMN2GAAKMT2A
SCHEMBL5958239 0.78 NPC1 (0.60) NPC1RAB9ASMN1; SMN2GAAKMT2A
SCHEMBL2047060 0.78 TSHR (0.48) NPC1RAB9ASMN1; SMN2GAAKMT2A
SCHEMBL2047059 0.78 TSHR (0.48) NPC1RAB9ASMN1; SMN2GAAKMT2A
SCHEMBL7623678 0.78 NPC1 (0.38) NPC1RAB9ASMN1; SMN2GAAKMT2A
SCHEMBL6569008 0.77
SCHEMBL2046493 0.76 NPC1 (0.46) NPC1RAB9ASMN1; SMN2GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE37839-E1 O-benzyloxime ethers and crop protection agents containing these compounds BASF AKTIENGESELLSCHAFT (DE) 2002-09-10 US disclosed
US-6326399-B1 CONTROLLING INSECTS, ARACHNIDS, NEMATODES BASF AKTIENGESELLSCHAFT (DE) 2001-12-04 US disclosed
US-6316459-B1 O-benzyloxime ethers and crop protection agents containing these compounds BASF AG (DE) 2001-11-13 US disclosed
US-6211190-B1 Pyrimidine derivatives, process and intermediate products for their preparation and pesticides or fungicides containing these derivatives BASF AKTIENGESELLSCHAFT (DE) 2001-04-03 US disclosed
CN-1161687-A Phenylacetic acid alkyl esters BASF AG (DE) 1997-10-08 CN disclosed