Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | AGXT | P21549 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691482 | 1.00 | IDO1 (0.46) | IDO1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL7630845 | 0.89 | NPC1 (0.41) | IDO1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2047059 | 0.87 | TSHR (0.48) | IDO1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2047060 | 0.87 | TSHR (0.48) | IDO1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2046492 | 0.85 | NPC1 (0.46) | IDO1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2046493 | 0.85 | NPC1 (0.46) | IDO1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL17180599 | 0.83 | IDO1 (0.46) | IDO1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL7623616 | 0.83 | NPC1 (0.39) | IDO1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL19039674 | 0.82 | NPC1 (0.44) | IDO1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2048931 | 0.82 | NPC1 (0.44) | IDO1NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316459-B1 | O-benzyloxime ethers and crop protection agents containing these compounds | BASF AG (DE) | 2001-11-13 | — | — | US | disclosed |
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |