Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7625075 | 0.82 | MCHR1 (0.51) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7633774 | 0.81 | GCG (0.46) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7623455 | 0.80 | F10 (0.53) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7631279 | 0.80 | SMN1; SMN2 (0.50) | BRD4MMP2MMP3MMP9MMP13 | |
| SCHEMBL7630885 | 0.79 | CD274 (0.55) | — | |
| SCHEMBL7632375 | 0.79 | NPC1 (0.53) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7626881 | 0.76 | HSP90AA1 (0.44) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7627770 | 0.74 | MCHR1 (0.58) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7627295 | 0.73 | AOC3 (0.47) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL28001720 | 0.71 | BRD4 (0.54) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907632-B1 | INHIBITION OF MATRIX METALLOPROTEASES BY SUBSTITUTED PHENETHYL COMPOUNDS | BAYER AG (US) | 2002-12-11 | — | — | EP | disclosed |