Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.51 |
| ▸ | MMP2 | P08253 | 3/20 | 0.48 |
| ▸ | MMP3 | P08254 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7623455 | 0.94 | F10 (0.53) | MCHR1MMP2MMP3MMP9MMP13 | |
| SCHEMBL7627770 | 0.92 | MCHR1 (0.58) | MCHR1MMP2MMP3MMP9MMP13 | |
| SCHEMBL7633774 | 0.91 | GCG (0.46) | MCHR1MMP2MMP3MMP9MMP13 | |
| SCHEMBL7632375 | 0.91 | NPC1 (0.53) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7631279 | 0.90 | SMN1; SMN2 (0.50) | MCHR1MMP2MMP3MMP9MMP13 | |
| SCHEMBL7633124 | 0.86 | LMNA (0.50) | MCHR1MMP2MMP3MMP9MMP13 | |
| SCHEMBL7626881 | 0.86 | HSP90AA1 (0.44) | MCHR1MMP2MMP3MMP9MMP13 | |
| SCHEMBL7630885 | 0.84 | CD274 (0.55) | ALDH1A1GAAKCNH2CYP2D6 | |
| SCHEMBL7630873 | 0.82 | BRD4 (0.42) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7634674 | 0.81 | SMN1; SMN2 (0.55) | MCHR1MMP2MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907632-B1 | INHIBITION OF MATRIX METALLOPROTEASES BY SUBSTITUTED PHENETHYL COMPOUNDS | BAYER AG (US) | 2002-12-11 | — | — | EP | disclosed |