SCHEMBL7631076

SCHEMBL7631076

CCCOC(COCCCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl)OCCC

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 1/20 0.32
S1PR1 P21453 1/20 0.32
S1PR3 Q99500 1/20 0.32
LPAR2 Q9HBW0 1/20 0.32
THRB P10828 1/20 0.32
HTT P42858 2/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7636757 0.99 HTT (0.31) S1PR2S1PR1S1PR3LPAR2THRB
SCHEMBL7628125 0.94 THRB (0.33) S1PR2S1PR1S1PR3LPAR2THRB
SCHEMBL7631115 0.93 HTT (0.33) S1PR2S1PR1S1PR3LPAR2THRB
SCHEMBL7634353 0.92 HTT (0.31) S1PR2S1PR1S1PR3LPAR2THRB
SCHEMBL6548484 0.91 HTT (0.32) HTT
SCHEMBL7637259 0.88 HTT (0.32) HTT
SCHEMBL7636813 0.87 MAPT (0.32) HTTMAPTHPGD
SCHEMBL7631847 0.87 HTT (0.33) HTT
SCHEMBL7634126 0.86 MAPT (0.33) HTTMEN1MAPTHPGDKMT2A
SCHEMBL7630714 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0888270-B1 DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2002-04-17 EP disclosed
US-6140274-A Dihalopropene compounds, their use as insecticides/acaricides and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-31 US disclosed
EP-0888270-A1 DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1999-01-07 EP disclosed
WO-1997028112-A1 DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-07 WO disclosed