SCHEMBL7631129

SCHEMBL7631129

C=CC(=O)OCCOCCOCCOc1ccc(C(C)(C)c2ccc(OCCOCCOCCOC(=O)C=C)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.60
ALDH1A1 P00352 9/20 0.53
TSHR P16473 3/20 0.53
TP53 P04637 2/20 0.53
HIF1A Q16665 2/20 0.53
HSD17B10 Q99714 1/20 0.53
KDM4E B2RXH2 10/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
GAA P10253 2/20 0.47
POLB P06746 2/20 0.45
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
HTT P42858 2/20 0.44
LMNA P02545 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12281676 1.00 THRB (0.60) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL19770675 1.00 THRB (0.60) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL6292051 1.00 THRB (0.60) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL16804047 1.00 THRB (0.60) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL16919771 1.00 THRB (0.60) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL137572 0.96 THRB (0.65) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL14173110 0.96 THRB (0.65) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL23607007 0.95 THRB (0.55) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL10033662 0.95 THRB (0.66) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL12430586 0.95 THRB (0.66) THRBALDH1A1TSHRTP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5942303-A CURABLE ADDITION TERPOLYMER BASED ON 2,2-BIS(P-(METH)ACRYLOYL -(P-(METH)ACRYLOYLOXY(ALKYLOXY)N-PHENYL)PROPANES, WHERE N IS 2-5, AND UNSATURATED COMPOUND; IMPACT STRENGTH; LOW SPECIFIC GRAVITY; LIGHTWEIGHT; EYEGLASSES; CONTACT LENSES; LENSES NOF CORPORATION (JP) 1999-08-24 US claimed
US-10647920-B2 Liquid crystalline composition, liquid crystal cured layer, method for producing same, and optical film ZEON CORPORATION (JP) 2020-05-12 US disclosed
US-20190225884-A1 LIQUID CRYSTALLINE COMPOSITION, LIQUID CRYSTAL CURED LAYER, METHOD FOR PRODUCING SAME, AND OPTICAL FILM ZEON CORPORATION (JP) 2019-07-25 US disclosed
US-9206350-B2 Composition comprising quantum dot, and device using same LMS CO., LTD. (KR) 2015-12-08 US disclosed
US-20150045499-A1 Composition Comprising Quantum Dot, and Device Using Same LMS CO., LTD. (KR) 2015-02-12 US disclosed
EP-0828167-B1 Resin composition for polymerization casting and optical material NOF CORP (JP) 2002-07-03 EP disclosed
US-5942303-A CURABLE ADDITION TERPOLYMER BASED ON 2,2-BIS(P-(METH)ACRYLOYL -(P-(METH)ACRYLOYLOXY(ALKYLOXY)N-PHENYL)PROPANES, WHERE N IS 2-5, AND UNSATURATED COMPOUND; IMPACT STRENGTH; LOW SPECIFIC GRAVITY; LIGHTWEIGHT; EYEGLASSES; CONTACT LENSES; LENSES NOF CORPORATION (JP) 1999-08-24 US disclosed
EP-0828167-A2 Resin composition for polymerization casting and optical material NOF CORPORATION (JP) 1998-03-11 EP disclosed