Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.41 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | DRD4 | P21917 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825129 | 0.88 | KMT2A (0.52) | KMT2AL3MBTL1NPFFR1NPFFR2DRD2 | |
| SCHEMBL7825124 | 0.88 | KMT2A (0.52) | KMT2AL3MBTL1NPFFR1NPFFR2DRD2 | |
| SCHEMBL7825126 | 0.88 | KMT2A (0.52) | KMT2AL3MBTL1NPFFR1NPFFR2DRD2 | |
| SCHEMBL8741001 | 0.88 | KMT2A (0.52) | KMT2AL3MBTL1NPFFR1NPFFR2DRD2 | |
| SCHEMBL19212166 | 0.84 | KMT2A (0.53) | KMT2AL3MBTL1NPFFR1NPFFR2DRD2 | |
| SCHEMBL7835003 | 0.84 | KMT2A (0.55) | KMT2AL3MBTL1NPFFR1NPFFR2DRD2 | |
| SCHEMBL3187533 | 0.84 | KMT2A (0.55) | KMT2AL3MBTL1NPFFR1NPFFR2DRD2 | |
| SCHEMBL3187519 | 0.84 | KMT2A (0.55) | KMT2AL3MBTL1NPFFR1NPFFR2DRD2 | |
| SCHEMBL7834998 | 0.84 | KMT2A (0.55) | KMT2AL3MBTL1NPFFR1NPFFR2DRD2 | |
| SCHEMBL1781856 | 0.84 | KMT2A (0.55) | KMT2AL3MBTL1NPFFR1NPFFR2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |