SCHEMBL7631970

SCHEMBL7631970

C=C[Si](CC)(CC)c1ccc(C(=O)OO[C]2CCC(CCCC)CC2)cc1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 2/20 0.34
TSHR P16473 2/20 0.34
CYP2C19 P33261 2/20 0.34
ALDH1A1 P00352 1/20 0.34
TLR4 O00206 1/20 0.32
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7628471 0.90 ALDH1A1 (0.34) CYP1A2CYP3A4TSHRCYP2C19ALDH1A1
SCHEMBL7630947 0.89
SCHEMBL7628498 0.88 CYP1A2 (0.33) CYP1A2CYP3A4TSHRCYP2C19ALDH1A1
SCHEMBL7626258 0.88 CYP1A2 (0.33) CYP1A2CYP3A4TSHRCYP2C19ALDH1A1
SCHEMBL7632272 0.86
SCHEMBL7629450 0.85 MEN1 (0.38) ALDH1A1
SCHEMBL7633349 0.85 CYP1A2 (0.35) CYP1A2CYP3A4TSHRCYP2C19ALDH1A1
SCHEMBL7628801 0.83 NPC1 (0.32) ALDH1A1
SCHEMBL7625115 0.82 NPC1 (0.32) ALDH1A1
SCHEMBL7626621 0.82 NPC1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed