Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7631975 | 1.00 | GRIA1 (0.56) | GRIA1ABCB1ARABCG2HTR2C | |
| SCHEMBL7631937 | 0.90 | GRIA1 (0.56) | GRIA1HTR2CHTR2AHTR2BCYP3A4 | |
| SCHEMBL7631933 | 0.90 | GRIA1 (0.56) | GRIA1HTR2CHTR2AHTR2BCYP3A4 | |
| SCHEMBL19166896 | 0.82 | GRIA1 (0.60) | GRIA1HTR2CHTR2AHTR2BKDM4E | |
| SCHEMBL6620367 | 0.81 | GRIA1 (0.53) | GRIA1HTR2CHTR2AHTR2BCYP2D6 | |
| SCHEMBL6620368 | 0.81 | GRIA1 (0.53) | GRIA1HTR2CHTR2AHTR2BCYP2D6 | |
| SCHEMBL8367071 | 0.80 | GRIA1 (0.52) | GRIA1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL8314975 | 0.80 | GRIA1 (0.82) | GRIA1KDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL31562981 | 0.80 | GRIA1 (0.60) | GRIA1ALDH1A1NPC1RAB9AHSD17B10 | |
| SCHEMBL31562998 | 0.80 | GRIA1 (0.60) | GRIA1ACHECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891365-B1 | BENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSES | UNIV CALIFORNIA (US) | 2002-10-16 | — | — | EP | disclosed |
| WO-1997036907-A9 | BENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE | — | 1997-12-04 | — | — | WO | disclosed |